Unicist Research: Closing the gap between macro and micro behavior

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The Unicist Research closed the gap between macro and micro behaviour. The unicist complexity research approach implies dealing with applications while researching, which requires that the lapse of research time be very long in order to achieve fully accurate predicted results before validating a hypothesis.

discoveries-unicist-2013-2014As it has been done every year since its foundation, The Unicist Research Institute synthesized this January the researches that had been finished until that time. After 38 years, 2013/2014, can be considered the year in which the integration of macro and micro behavior could be confirmed.

The gap between the macro and the micro cosmos has been and is still a problem that theoretical physicists are closing. The integration of the field of macro and micro behavior, that has been solved by Peter Belohlavek, is homologous. It allows integrating social behavior with individual behavior, making human complex adaptive systems manageable.

The publication of Conceptual Economics, Conceptual Anthropology and Conceptual Psychology are some of the milestones of this process that included the researches developed in 2013-2014 (see image above).

You can access Conceptual Economics and Conceptual Anthropology at:
http://www.unicist.org/repo/#Economy

If you want to access the “Drivers of Human Behavior” that explain the structure of human intelligence, please access: www.unicist.org/repo/#Psychology

Unicist Press Committee

NOTE: The Unicist Research Institute was the pioneer in using the unicist logical approach in complexity science research and became a private global decentralized leading research organization in the field of human adaptive systems. It has an academic arm and a business arm. http://www.unicist.org/repo/#Unicist


Proteins and Amino Acids: Discovery of the Unicist Ontology of Amino Acids

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The Unicist Ontology of amino acids allows understanding its functionality and the possibilities of their integration to build proteins. Their purpose is given by the side chain which defines the different functions amino acids can fulfill.

Amino Acids

It has to be considered that the Unicist Ontology emulates the ontogenetic intelligence of nature that was discovered which defines that there is always a purpose, an active and entropic principle and an energy conservation principle. The unicist ontology of amino acids is a demonstration of how this intelligence works.

The active function of an amino acid is given by the carboxyl group that establishes a supplementary relationship with the R-group. The energy conservation function is given by the amino group, which establishes a complementary relationship with the R-group.

Amino acids are biologically organic compounds integrated by amine and carboxylic functional groups, driven by a side-chain specific to each amino acid. The key elements of an amino acid are carbon, hydrogen, oxygen, and nitrogen, though other elements are found in the side-chains of some amino acids.

Amino acids are the building blocks of peptides and proteins. They are composed of amine and carboxylic acid groups, separated by the alpha-carbon but the side chains on the alpha carbon vary with the acid. They are the subunits of proteins: amino acids make peptide chains, peptide chains make polypeptides, polypeptides make proteins.

Amino Acid StructureAmino acids are the structural units that build proteins. They join together to form short polymer chains called peptides or longer chains called either polypeptides or proteins. These polymers are linear and unbranched, with each amino acid within the chain attached to two neighboring amino acids.

Peptide Formation

Amides can be thought of as forming from the reaction of an amine and a carboxylic acid. In the same way, two amino acids can combine to form a dipeptide, held together by a peptide bond.

Peptides

A fourth amino acid would form a tetrapeptide, a fifth would form a pentapeptide, and so on. Short chains are referred to as peptides, chains of up to about 50 amino acids are polypeptides, and chains of more than 50 amino acids are proteins. Amino acids in peptide chains are called amino acid residues.

Classification of Amino Acids

Acidic amino acids and their amides: aspartic acid, asparagine, glutamic acid, glutamine.

Basic amino acids: histidine, lysine, arginine.

Aromatic amino acids: phenylalanine, tyrosine, tryptophan.

Sulfur containing amino acids: cysteine, methionine.

Imido acid: proline.

Hydrophobic side chains: glycine, alanine, valine, leucine, isoleucine.

Hydroxylic amino acids: serine, threonine, (tyrosine).

Learn more about amino acids at: http://www.biology.arizona.edu/biochemistry/problem_sets/aa/aa.html

Unicist Press Committee

NOTE: The Unicist Research Institute was the pioneer in using the unicist logical approach in complexity science research and became a private global decentralized leading research organization in the field of human adaptive systems. It has an academic arm and a business arm.
https://www.unicist.org/healthcare/wp-content/uploads/2015/02/turi.pdf


Abstract: Discovery of the Unicist Ontology of Health

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The research on the unicist ontology of health, which began in 2001, was focused on finding the essential structure of health that allows understanding the multiple medical specialties and medical approaches that deal with “the art of healing”. This research was developed at The Unicist Research Institute and was led by Peter Belohlavek.

Paradoxically, it could be finished after the ontological structures of healthcare were discovered. This research integrated health and medical approaches in a “unified field”. The previous researches that sustained this discovery were:

Unicist Ontology of Health-The Unified Field of Healthcare
-Homology between Concepts and Stem Cells
-The Ontogenetic Intelligence of Nature
-The Fallacy of Organs and  Chronic Diseases
-The Unicist Structure of Viruses
-The Ontogenetic Map of Chronic Diseases
-The Ontogenetic Map of Addictions
-The Ontogenetic Map of Stress
-The Ontogenetic Map of Cures
-The Ontogenetic Map of Immune Systems
-The Ontogenetic Map of Therapeutics
-The Ontogenetic Map of Diseases

Health can be defined as the integration of organic functionality, psychic functionality and the functionality of the inner energy flow.

The organic functionality is defined by the functionality of organs which, working as complex adaptive systems, can only be measured based on the consequences of their function. Organic functionality also includes the functionality of inner systems, although they cannot be considered as organs (e.g: the immune system). The fallacy of organs functionality is a proof of the limits of the possibilities of organic functionality.
http://www.unicist.org/healthcare/unicist-ontology-of-health-the-fallacies-of-organs/

The psychic functionality is defined by the functionality of the instinctive, spiritual and psychological processes whether they are conscious or unconscious that allow individuals to adapt to the environment. The psychic functionality deals with the interpersonal and intrapersonal adaptive processes and with the meaning of life.

The energy-flow functionality can only be measured by the consequences of its lack of functionality. It implies that the human being considered as a system flows internally in a harmonic way. This allows individuals to live and adapt to the environment.

Fostering health requires ensuring that the psychic functionality, which is the active function of health, maintains and does not hinder the energy flow that sustains the functionality of organs. Fostering health requires stimulating a meaningful life where the interpersonal and intrapersonal adaptation conflicts can be managed.

Unicist Press Committee

NOTE: The Unicist Research Institute was the pioneer in using the unicist logical approach in complexity science research and became a private global decentralized leading research organization in the field of human adaptive systems. It has an academic arm and a business arm.
https://www.unicist.org/healthcare/wp-content/uploads/2015/01/turi.pdf


Adaptive clinical trials: An upgrade and energy saving methodology

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The discovery of the unicist ontological structure of complex systems developed at The Unicist Research Institute provided the final input to develop a methodology for adaptive clinical trials. The unicist ontology of health that was discovered provided the basic background for this methodology: http://goo.gl/Ruwsr3

Clinical TrialsThis approach is based on the integration of aspects of traditional clinical trials, the concept of the “learn and confirm” standard and the unicist approach to complexity sciences.

This approach is based on the use of destructive tests, which are a special kind of falsification test (Karl Popper), to sustain the Phase I and Phase II clinical trials.

The objective of destructive tests is to confirm the limits of the functionality that is being tested.

They are necessary in the previous research work but their application in these phases allows providing a safe input to develop the following phases. Destructive tests are based on universal experimenting and on the knowledge of the conceptual foundations of what is being researched.

Clinical TrialsPhase III and IV are approaches that use non destructive tests that are analogous to the traditional clinical trials but with the inclusion of a quality assurance process that triggers a “learning” process when predefined limits are exceeded.

The “learn & confirm” methodology introduced at Wyeth changed the paradigms of clinical trials and introduced a conceptual simplification in the R&D processes that could not expand massively because of the non-evident economic benefits of this technology.

The unicist approach to adaptive clinical trials is an approach based on the complexity science research methodology developed at The Unicist Research Institute that simplified the discovery-learn-confirm method introduced by Wyeth and provides a secure approach to life-sciences.

A research consortium, coordinated by Peter Belohlavek, is being organized to develop this solution in real application fields. It is expected that this methodology becomes a standard within the next two years based on the shortening of the R&D processes and the saving of up to 50% of the costs.

Learn more about “What are complexity sciences” at:
http://www.unicist.org/repo/#Unicist

Unicist Press Committee

NOTE: The Unicist Research Institute was the pioneer in using the unicist logical approach in complexity science research and became a private global decentralized leading research organization in the field of human adaptive systems. It has an academic arm and a business arm.
https://www.unicist.org/healthcare/wp-content/uploads/2014/10/turi.pdf


Logical Management Tools: Unicist Reflection for Problem Solving

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reflectionUnicist reflection is an approach to complex human adaptive systems to understand their nature, define the possibilities to influence them, apprehend the algorithms that allow exerting influence and generate added value.

Unicist reflection has no relationship with other introspective approaches like religious introspection, transcendent meditation, yoga or other technologies that have been developed for different purposes.

Unicist Reflection has been developed to deal with complex human adaptive systems, such as businesses, to develop scenarios, diagnoses and strategies to achieve possible results.

Reflection covers five stages before reaching the environment adaptation and the influence upon it.

1) It reflects outside
Projecting the prejudices we have onto reality.
2) It reflects inside
Introjecting the reality elements we try to exert some influence upon.
3) The outside vanishes
Focusing on the reality we try to exert some influence upon.
4) The inside vanishes
Making the specific reality universal.
5) All is one

The “reflecting outside” stage deals with the projection of our own preconceptions and implies comparing them with the reality facts or with other people’s preconceptions.

Reality is introjected to be able to influence the environment. The aim is to develop a strategy which allows influencing while being influenced.

Once we are in peace with the environment we start to focus on the influence we try to exert.

When we have developed a diagnosis, it has a universal implicit character. This means that it responds to universal elements. This allows transferring the knowledge to other homologous fields and originates the conceptual “benchmarking”.

When this level is reached, we will comprehend the universality of concepts.

The Unicist Reflection process can be synthesized in the following steps:

0 – Focus on the solution
1 – Dealing with projections
– Destructive pilot tests
2 – Dealing with Introjections
– Non-destructive – Destructive pilot tests
3 – Dealing with integration
– Non-destructive pilot tests
4 – Dealing with communion
– Results validation
5 – Dealing with the unified field

A Unicist Reflection process implies leaving behind the labyrinth of one’s opinions and operational shortcuts. It requires knowledge, courage and humbleness.

Learn more about the Logical Management Tools at:
http://www.unicist.net/management-tools.php

Diego Belohlavek

NOTE: The Unicist Research Institute was the pioneer in using the unicist logical approach in complexity science research and became a private global decentralized leading research organization in the field of human adaptive systems. It has an academic arm and a business arm.
https://www.unicist.org/healthcare/wp-content/uploads/2014/08/turi.pdf


Exploring the possibility of participating in a Think Tank

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This is an invitation for MDs, from all over the world, to participate in what is the next stage in healthcare which is driven by the unicist logic based and object driven technologies.

Unicist Basic Discoveries applied to HealthcareWe invite MDs who are open to deal with the new stage in behavioral sciences applied to healthcare to work in projects dealing with the implementation of adaptive healthcare processes. These projects are developed by Think Tanks in which they would participate. There are sponsored learning programs on the unicist logical approach for the participants.

The discoveries made at The Unicist Research Institute allowed emulating the nature of healthcare processes and establishing adaptive object driven processes that integrate medical practice with management.

We strongly suggest you compare this approach to the complex adaptive aspects of healthcare businesses with alternative technologies:

Compare with our Colleagues

If you are interested, please contact us so we can provide more information at:
n.i.brown@unicist.org

Executive Committee

NOTE: The Unicist Research Institute was the pioneer in using the unicist logical approach in complexity science research and became a private global decentralized leading research organization in the field of human adaptive systems. It has an academic arm and a business arm.
https://www.unicist.org/healthcare/wp-content/uploads/2014/07/turi.pdf


Unicist Ontology of Health: The Fallacies of Organs

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The unicist ontology of fallacies and a particular case of the fallacies of organs will be introduced following a synthetic description on the fallacious behavior of the kidneys and its consequences in the human body.The case of the fallacious behavior of kidneys will be presented as an example for its consequences in the human body.

The fallacies of organs are either movement or inaction fallacies. They are natural responses when the survival of the object-organ is being threatened by the “system” that pretend to ensure the survival of the organ in spite of the consequences on the whole body.

The synthetic description of the case of kidney fallacies will provide the understanding of how the fallacious behavior occurs.

Fallacy of Kidney’s Behavior

The kidney generates fallacious responses when it is threatened by dysfunctional blood flow. The kidney decides to survive itself in spite of the consequences on the organism.

Pre renal kidney failure is caused by conditions or substances that interfere with blood flow to the kidneys. Conditions that may leave the kidneys with insufficient blood flow or blood supply include:

Low blood pressure: Low blood pressure can be caused by severe bleeding, infection, dehydration, or shock.

Reduced blood flow: Reduced blood flow to the kidney can be caused by a weak heart, heart attack, or congestive heart failure.

Low blood volume: Low blood volume can be caused by severe dehydration and an excessive loss of fluid, which decreases the volume of blood and the amount of blood available to the kidneys.

High blood pressure makes the heart work harder and, over time, can damage blood vessels throughout the body. If the blood vessels in the kidneys are damaged, they may stop removing wastes and extra fluid from the body. The extra fluid in the blood vessels may then raise blood pressure even more. It’s a dangerous cycle.

High blood pressure is one of the leading causes of kidney failure, also called end-stage renal disease (ESRD). People with kidney failure must either receive a kidney transplant or have regular blood-cleansing treatments called dialysis. Every year, high blood pressure causes more than 25,000 new cases of kidney failure in the United States.

The fallacies of the kidney drive to chronic diseases or to destroying the organism and dying with it.

Conclusion

One of the consequences of systematic fallacious behavior is the generation of chronic dysfunctions of the organ. If the problem of blood pressure is not equilibrated, the kidney will tend to change its functionality which will hinder the fulfillment of its purpose.

Peter Belohlavek

NOTE: The Unicist Research Institute was the pioneer in using the unicist logical approach in complexity science research and became a private global decentralized leading research organization in the field of human adaptive systems. It has an academic arm and a business arm.
https://www.unicist.org/healthcare/wp-content/uploads/2014/06/turi.pdf


Social viruses produce paradoxical results in businesses

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Social viruses are the consequence of the use of anti-intelligence. Anti-intelligence is a “virus”. Anti-intelligence is the use of intelligence without ethical purposes. It substitutes ethical intelligence with a utopia (this utopia is homological with to proteins viruses use).

The mutation of social viruses is produced by the functionality or dysfunctionality that the utopia poses in the environment. If the utopia can take advantage of the conditions of the environment there is no need to change. If it is dysfunctional, then utopias change and thus the complete structure of the social virus mutates.

The Destruction Power of Social Viruses

We have discovered four levels of jeopardy of viruses:

  1. Social viruses that install in a social entity but remain as marginal elements that validate the structure of the institution or culture.
  2. Social viruses that work at a lower or different ethical level that degrade the institutional or cultural activity.
  3. Social viruses that work at a lower, different and incompatible ethical level that provoke an extreme degradation of the institutional or cultural activity.
  4. Social viruses that work at an incompatible ethical and functional level that provoke the destruction of the institutional and cultural perception. They provoke a “back to individualism” effects.

Diana Belohlavek

NOTE: The Unicist Research Institute was the pioneer in using the unicist logical approach in complexity science research and became a private global decentralized leading research organization in the field of human adaptive systems. It has an academic arm and a business arm.
http://www.unicist.org/repo/#Unicist


The Organization of Patient Centered Management R&D Groups

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We are installing Patient Centered Management in Healthcare Organizations. This implies a re-launching of the applied research activities of The Unicist Research Institute that will be developed as in-company research groups or outsourced activities. The organization of these groups will be adapted to the legal regulations of each country.

Healthcare R&D Groups

To request more information please contact: n.i.brown@unicist.org

Applied Research Committee

NOTE: The Unicist Research Institute was the pioneer in using the unicist logical approach in complexity science research and became a private global decentralized leading research organization in the field of human adaptive systems. It has an academic arm and a business arm. http://www.unicist.org/repo/#Unicist


Our best wishes for 2014: Happy New Year!

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“Cooperation in Diversity” is much more than our motto. It is a way of living.

Happy New Year 2014

Make your wishes come true.
Have a happy New Year!

The Unicist Research Institute