An ontological approach to adaptive clinical trials


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Human cures belong to the field of complexity sciences. Complexity sciences have been developed to research the field of adaptive systems.

The “Learn and Confirm” method started by Wyeth introduced an implicit ontological approach to clinical trials’ work process considering them as adaptive systems.

Complex adaptive systems need to be researched with a “learn and confirm” method.  The objective is to end the research having discovered the foundations of the behavior of an adaptive system.

Ontological research action is based on real experiencing. That is what clinical trials do. They try to confirm the foundations that have been given as valid. To do so they need to be based on secure knowledge to allow learning in the field the knowledge is being acquired.

This process needs to be recycled until the foundations are secure. This is what adaptive clinical trials are about.

Learn more:
https://www.unicist.org/healthcare/wp-content/uploads/2011/04/rbcr0023t.pdf

Learn more about the trend of ontology based solutions for businesses:
http://www.unicist.net/obs.shtml

Request more information: n.i.brown@unicist.org

Peter Belohlavek

NOTE: The Unicist Research Institute is the major research organization in the world in its specialty based on more than 3,500 researches in complexity science, developed since 1976 until September 2010,  applied to individual, institutional and social evolution. The applicative researches are based on the discovery of the Ontogenetic Intelligence of Nature and the consequent Unicist Theory of Evolution.

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